Nattokinase is a powerful natural enzyme that has been extracted from a traditional Japanese food called natto (fermented soybean paste). Nattokinase has fibrinolytic activity it degrades a substance in our blood called fibrin. This is how it is able to support our overall cardiovascular health. NSK-SD nattokinase is made in Japan, using non-GMO soybeans and has had all vitamin K removed.Recommended Dosage: Take 1 capsule once daily preferably before bedtime.Caution: Do not use if you 1) are pregnant or breastfeeding 2) are taking health products that affect blood coagulation 3) have a bleeding disorder. Consult a health care practitioner for use beyond 4 weeks. Consult a health care practitioner if you 1) have a cardiovascular, kidney or liver disorder 2) are taking any medications. Stop using this product 7 days before any scheduled surgery, or immediately if you have unscheduled surgery or if you suffer from an injury resulting in bruising or bleeding. This product is derived from soy. Do not use if you have a soy allergy.